The main manifestations are epigastric pain or burning sensation, epigastric fullness and early satiety after meals, which may be accompanied by loss of appetite, belching, nausea or vomiting.
The etiology of dyspepsia is complex, and the common cause is insufficient secretion or decreased function of digestive enzymes. Whether it is functional dyspepsia or organic dyspepsia, supplementing digestive enzyme preparations is an important and commonly used treatment measure, which can improve Indigestion symptoms such as epigastric fullness and anorexia.
At present, the commonly used digestive enzyme preparations in domestic clinical practice include multi-enzyme tablets, trypsin enteric-coated capsules, compound digestive enzyme capsules, compound azinamide enteric-coated tablets and Aspergillus oryzae trypsin tablets, etc.
So, in the face of many varieties of enzyme preparations, how should we distinguish and choose?
1- Pepsin
It is a proteolytic enzyme extracted from the gastric mucosa of pigs, cattle or sheep, which can decompose large molecular proteins into small molecular hydrazones and peptones, but cannot be further decomposed into amino acids. When the pH value of this type of drug is 1.6-1.8 It has the strongest effect and is destroyed and inactivated in an alkaline environment.
2- Trypsin
It is a mixture of enzymes extracted from pig, sheep or bovine pancreas. Including trypsin, pancreatic amylase, pancreatic lipase and so on. Among them, trypsin is responsible for converting protein components in food into peptone, trypsin can convert starchy food into dextrin and sugar, and pancreatic lipase breaks down fat in food into glycerol and fatty acids. Because pancreatin needs to exert its curative effect in an alkaline or neutral environment, it needs to use enteric solvent type. Enteric coating can protect pancreatin from being damaged by strong acidic gastric juice, so that it can play a role in intestinal juice.
3- Papain
It can hydrolyze animal and vegetable protein to improve protein utilization.
4- Cellulase
It can degrade plant cell walls, promote the digestion and absorption of nutrients, and activate pepsin.
5- Lactase
Can hydrolyze lactose to produce glucose and galactose, mainly for lactose intolerant people